Human TRiC complex in closed state with nanobody bound (Consensus Map)
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 7nvl
Q-score: 0.631
Kelly JJ, Tranter D, Pardon E, Chi G, Kramer H, Happonen L, Knee KM, Janz JM, Steyaert J, Bulawa C, Paavilainen VO, Huiskonen JT, Yue WW
Nat Struct Mol Biol (2022) 29 pp. 420-429 [ Pubmed: 35449234 DOI: doi:10.1038/s41594-022-00755-1 ]
- T-complex protein 1 subunit gamma (60 kDa, Protein from Human)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Human)
- T-complex protein 1 subunit theta (59 kDa, Protein from Human)
- T-complex protein 1 subunit delta (57 kDa, Protein from Human)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Human)
- Magnesium ion (24 Da, Ligand)
- T-complex protein 1 subunit eta (59 kDa, Protein from Human)
- Human tric complex with nanobody bound (Complex)
- T-complex protein 1 subunit beta (57 kDa, Protein from Human)
- Nanobody nb18 (Complex from Lama glama)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Aluminum fluoride (83 Da, Ligand)
- Water (18 Da, Ligand)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Human)
- Nanobody nb18 (14 kDa, Protein from Lama glama)
- Human type ii chaperonin tric/cct complex (Complex from Homo sapiens)
Human TRiC complex in closed state with nanobody Nb18, actin and PhLP2A bound
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7nvm
Q-score: 0.529
Kelly JJ, Tranter D, Pardon E, Chi G, Kramer H, Happonen L, Knee KM, Janz JM, Steyaert J, Bulawa C, Paavilainen VO, Huiskonen JT, Yue WW
Nat Struct Mol Biol (2022) 29 pp. 420-429 [ Pubmed: 35449234 DOI: doi:10.1038/s41594-022-00755-1 ]
- T-complex protein 1 subunit alpha (60 kDa, Protein from Human)
- T-complex protein 1 subunit delta (57 kDa, Protein from Human)
- Aluminum fluoride (83 Da, Ligand)
- T-complex protein 1 subunit eta (59 kDa, Protein from Human)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- T-complex protein 1 subunit beta (57 kDa, Protein from Human)
- T-complex protein (Complex from Homo sapiens)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Homo sapiens)
- Nanobody (Complex from Lama glama)
- T-complex protein 1 subunit theta (59 kDa, Protein from Human)
- Actin, cytoplasmic 2 (41 kDa, Protein from Human)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- Phosducin-like protein 3 (27 kDa, Protein from Human)
- Human type ii chaperonin tric/cct (Complex from Homo sapiens)
- Human type ii chaperonin tric/cct complex with nanobody nb18, actin and phlp2a bound (Complex)
- Magnesium ion (24 Da, Ligand)
- Water (18 Da, Ligand)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Human)
- Nanobody nb18 (14 kDa, Protein from Lama glama)
Human TRiC complex in closed state with nanobody and tubulin bound
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7nvn
Q-score: 0.558
Kelly JJ, Tranter D, Pardon E, Chi G, Kramer H, Happonen L, Knee KM, Janz JM, Steyaert J, Bulawa C, Paavilainen VO, Huiskonen JT, Yue WW
Nat Struct Mol Biol (2022) 29 pp. 420-429 [ Pubmed: 35449234 DOI: doi:10.1038/s41594-022-00755-1 ]
- T-complex protein 1 subunit gamma (60 kDa, Protein from Human)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Human)
- T-complex protein 1 subunit theta (59 kDa, Protein from Human)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit delta (57 kDa, Protein from Human)
- Human type ii chaperonin tric/cct complex with nanobody nb18 and tubulin bound (Complex)
- Nanobody (14 kDa, Protein from Lama glama)
- T-complex protein 1 subunit epsilon (Complex from Homo sapiens)
- T-complex protein 1 subunit eta (59 kDa, Protein from Human)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- T-complex protein 1 subunit beta (57 kDa, Protein from Human)
- Magnesium ion (24 Da, Ligand)
- Aluminum fluoride (83 Da, Ligand)
- Water (18 Da, Ligand)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Human)
- Human type ii chaperonin tric/cct complex (Complex from Homo sapiens)
- Nanobody (Complex from Lama glama)
- Tubulin beta-2a chain (49 kDa, Protein from Human)
Human TRiC complex in open state with nanobody bound
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7nvo
Q-score: 0.502
Kelly JJ, Tranter D, Pardon E, Chi G, Kramer H, Happonen L, Knee KM, Janz JM, Steyaert J, Bulawa C, Paavilainen VO, Huiskonen JT, Yue WW
Nat Struct Mol Biol (2022) 29 pp. 420-429 [ Pubmed: 35449234 DOI: doi:10.1038/s41594-022-00755-1 ]
- T-complex protein 1 subunit theta (59 kDa, Protein from Human)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Human)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Human)
- Human type ii chaperonin tric/cct complex with nanobody bound (Complex)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Homo sapiens)
- T-complex protein 1 subunit delta (57 kDa, Protein from Human)
- Nanobody (14 kDa, Protein from Lama glama)
- Magnesium ion (24 Da, Ligand)
- T-complex protein 1 subunit eta (59 kDa, Protein from Human)
- Nanobody nb18 (Complex from Lama glama)
- T-complex protein 1 subunit beta (57 kDa, Protein from Human)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Aluminum fluoride (83 Da, Ligand)
- Water (18 Da, Ligand)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Human)
- Human type ii chaperonin tric/cct complex (Complex from Homo sapiens)